Acute conduction velocity changes in guinea-pigs after administration of diphenylhydantoin.

نویسندگان

  • P M Le Quesne
  • V Goldberg
  • F Vajda
چکیده

Motor nerve conduction velocity was measured after dosing guinea-pigs with 200-400 μmol/kg diphenylhydantoin (DPH) daily for three to four days. Conduction velocity fell by a mean value of 13% in animals that achieved plasma DPH levels over 200 μmol/l. There was no change in velocity with DPH levels below this value.

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عنوان ژورنال:
  • Journal of neurology, neurosurgery, and psychiatry

دوره 39 10  شماره 

صفحات  -

تاریخ انتشار 1976